Anticancer agent 253 [1983924-33-9]
HY-116904
CAS Number1983924-33-9
Product group Chemicals
Molecular Weight500.51
Overview
- SupplierMedChem Express
- Product NameAnticancer agent 253 [1983924-33-9]
- Delivery Days Customer9
- CAS Number1983924-33-9
- CertificationResearch Use Only
- Molecular FormulaC29H23F3N4O
- Molecular Weight500.51
- Scientific DescriptionAnticancer agent 253 (Compound 26) has anti-cancer activity against breast cancer cells, with IC50s of 6 microM (MCF-7), 10 microM (MDA-MB-231) and 6.4 microM (4T1 cells). Anticancer agent 253 arrests cell cycle and induces mitochondria-mediated apoptosis in cancer cells. Anticancer agent 253 inhibits Akt phosphorylation in human breast and prostate cancer[1].
- SMILESO=C(/C(CN(C/1)CC2=CN(N=N2)CC3=CC=C(C=C3)F)=C/C4=C(C=CC=C4)F)C1=C\C5=C(C=CC=C5)F
- UNSPSC12352200