Anticancer agent 63 [2529657-32-5]

MedChem Express

Anticancer agent 63 [2529657-32-5]

10

2529657-32-5

Research Use Only

C17H24F3NOSe

394.33

Anticancer agent 63 (compound 3h) shows active in reducing the viability of different cancer cell lines, including SW480, HeLa, A549 and MCF-7, with IC50 values at 24 h of 4.9, 11.5, 9.4, and 3.4 microM, respectively. Anticancer agent 63 induce apoptosis in MCF-7 cells via down-regulating the expression of Bcl-2 and up-regulating the expression of IL-2 and Caspase-3. Anticancer agent 63 also shows antioxidant activity[1].

CC(CC1=CC=C(C=C1)C(C(NCCC[Se]C(F)(F)F)=O)C)C

12131703