Antimicrobial agent-1 [2579696-45-8]

MedChem Express

Antimicrobial agent-1 [2579696-45-8]

10

2579696-45-8

Research Use Only

C22H21N3O2S

391.49

Antimicrobial agent-1 (compound 6C) possesses potent activity against TolC mutant E. coli with an MIC value of 2 microg/mL. Antimicrobial agent-1 and Colistin exhibit synergistic activity against Gram-negative bacteria. Antimicrobial agent-1 has no cytotoxicity on mammalian cell lines, with MICs > 128 microg/mL in Caco-2 and Vero cell lines[1].

CS(=O)(NC1=CC=CC(C2=NC3=CC=CC=C3N2CC4=CC=C(C)C=C4)=C1)=O

12131703