Antipain . dihydrochloride [37682-72-7]

AdipoGen Life Sciences

Antipain . dihydrochloride

10

37682-72-7

Research Use Only

>97%

C27H44N10O6 . 2HCl

604.7 . 72.9

Chemical. CAS: 37682-72-7. Formula: C27H44N10O6 . 2HCl. MW: 604.7 . 72.9. Synthetic. Potent reversible inhibitor of serine/cysteine proteases and some trypsin-like proteases. Inhibits papain, trypsin and trypsin-like serine proteases as well as cathepsin A, B and D. Similar activity spectrum comparable to leupeptin (AG-CP3-7000). Acts by forming a hemiacetal adduct between its aldehyde group and the active serine of the proteinase. Inhibits transformation of NIH3T3 cells after transfection with an activated H-ras oncogene. Used to evaluate the role of proteases in the process of malignant cell transformations. Shows antibacterial and antiparasitic activity. - Potent reversible inhibitor of serine/cysteine proteases and some trypsin-like proteases. Inhibits papain, trypsin and trypsin-like serine proteases as well as cathepsin A, B and D. Similar activity spectrum comparable to leupeptin (AG-CP3-7000). Acts by forming a hemiacetal adduct between its aldehyde group and the active serine of the proteinase. Inhibits transformation of NIH3T3 cells after transfection with an activated H-ras oncogene. Used to evaluate the role of proteases in the process of malignant cell transformations. Shows antibacterial and antiparasitic activity.

[Cl-].[Cl-].[H]C(=O)C(CCCNC(N)=[NH2+])NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)NC(CC1=CC=CC=C1)C(O)=O)C(C)C

-20°C,2°C to 8°C

12352200