Antiproliferative agent-6 [2389016-82-2]

MedChem Express

Antiproliferative agent-6 [2389016-82-2]

10

2389016-82-2

Research Use Only

C21H14ClFN6

404.83

Antiproliferative agent-6 (compound 8a) is a potent antitumor agent. Antiproliferative agent-6 has antiproliferative activity against cancer cell lines HCT116, MCF-7, H460 and non-tumor aneuploid immortal keratinocyte HaCaT cells with GI50s of 0.5 microM, 2 microM, 0.7 microM and 3.5 microM, respectively[1].

N#CC1=C(C2=C(N3C1=NC4=C3C=CC=C4)C=C(C=C2)F)N5C=C(N=N5)CCCCl

12131703