Antitrypanosomal agent 12

MedChem Express

Antitrypanosomal agent 12

10

Research Use Only

C49H77N2NaO10S

909.20

Antitrypanosomal agent 12 is a C20-phenylthiourea with trypanocidal and cytotoxic activities. Antitrypanosomal agent 12 shows antitrypanosomal activity with 50% growth inhibition (GI50) values of 0.22 microM. Antitrypanosomal agent 12 induces faster cell swelling in bloodstream-form trypanosomes than Salinomycin (HY-15597)[1].

CC[C@H]([C@@H]1[C@@H](C)C[C@@H](C)[C@@]2(CC[C@H](NC(NC3=CC=CC=C3)=S)[C@@]4(O[C@@]([C@@H]5O[C@@H](C)[C@@](O)(CC)CC5)(C)CC4)O2)O1)C([C@H]([C@@H](O)[C@H](C)[C@]6([H])O[C@@H]([C@H](C(O[Na])=O)CC)CC[C@@H]6C)C)=O

12131703