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Antitrypanosomal agent 4 [2456427-48-6]

HY-146049
MedChem Express
CAS Number2456427-48-6
Product group Chemicals
Molecular Weight419.84
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Antitrypanosomal agent 4 [2456427-48-6]
  • Delivery Days Customer
    10
  • CAS Number
    2456427-48-6
  • Certification
    Research Use Only
  • Molecular Formula
    C18H14ClN3O5S
  • Molecular Weight
    419.84
  • Scientific Description
    Antitrypanosomal agent 4 (compound 19) is a potent and blood-brain barrier permeable antitrypanosomal agent. Antitrypanosomal agent 4 has good activity against Trypanosoma cruzi (T. cruzi) and Trypanosoma brucei brucei (T. b. brucei) with IC50s of 1.2 microM and 70 nM, respectively[1]. Antitrypanosomal agent 4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • SMILES
    OCCC#CC1=CC(Cl)=CN2C1=NC(CS(=O)(C3=CC=CC=C3)=O)=C2[N+]([O-])=O
  • UNSPSC
    12131703