Antitumor agent-48

MedChem Express

Antitumor agent-48

10

Research Use Only

C35H34N2O14

706.65

Antitumor agent-48 (Compound 4a) is a 2,3-dehydrosilybin derivative with an antitumor activity. Antitumor agent-48 shows cytotoxic activity against MCF-7, NCI-H1299, HepG2 and HT29 cells with IC50 values of 8.06 microM, 13.1 microM, 16.51 microM and 12.44 microM, respectively[1].

COC1=CC(C2OC3=C(OC2CO)C=CC(C4=C(C(C5=C(C=C(C=C5O4)OC(N6CCOCC6)=O)O)=O)OC(N7CCOCC7)=O)=C3)=CC=C1O

12352200