Antitumor agent-49 [2763914-21-0]

MedChem Express

Antitumor agent-49 [2763914-21-0]

10

2763914-21-0

Research Use Only

C42H41BrN4O8S

841.77

Antitumor agent-49 (Compound 10) is a Harmine derivative-furoxan hybrids containing NO donor, with antitumor activities. Antitumor agent-49 shows cytotoxic activity against HepG2 cells with an IC50 of 1.79 microM. Antitumor agent-49 produces high levels of NO in vitro[1].

CC1=[N+](C=CC2=C1N(C3=C2C=CC(OCC(OCCCCOC4=NO[N+]([O-])=C4S(=O)(C5=CC=CC=C5)=O)=O)=C3)CCCC6=CC=CC=C6)CC7=CC=CC=C7.[Br-]

12131703