Antitumor agent-60 [865784-65-2]

MedChem Express

Antitumor agent-60 [865784-65-2]

10

865784-65-2

Research Use Only

C24H28O10S

508.54

Antitumor agent-60 (compound 20) is a potent antitumor agent, targeting RAS-RAF signaling pathway and binding to CRAF with a Kd value of 3.93 microM. Antitumor agent-60 induces apoptosis by blocking cell cycle at G2/M phase. Antitumor agent-60 enhances the level of p53 and ROS. Antitumor agent-60 causes oval and irregular nucleus in cancer cells. Antitumor agent-60 can suppress the growth of tumor to some extent in A549 xenograft model[1].

COC1=CC(OC)=C(C(OC)=C1)/C=C/S(=O)(CC2=CC=C(C(OC(CCCC(O)=O)=O)=C2)OC)=O

12131703