Antitumor agent-61 [2408917-12-2]
HY-146080
Overview
- SupplierMedChem Express
- Product NameAntitumor agent-61 [2408917-12-2]
- Delivery Days Customer10
- CAS Number2408917-12-2
- CertificationResearch Use Only
- Molecular FormulaC54H63FN5O10P
- Molecular Weight992.08
- Scientific DescriptionAntitumor agent-61 (Compound 9b), Irinotecan (Ir) derivative, is a potential antitumor agent. Antitumor agent-61 displays potent activity with IC50s of 0.92, 1.39, 1.75, 2.20, 3.05 and 3.23 microM against five human cancer cells SK-OV-3, SK-OV-3/CDDP, U2OS, MCF-7, A549 and MG-63, respectively. Antitumor agent-61 induces SK-OV-3 cells apoptosis through mitochondrion pathways[1].
- SMILESO=C(N1CCC(CC1)N2CCCCC2)OC3=CC4=C(CC)C5=C(C6=CC7=C(COC(C7(CC)OC(CCCC8=CC=C(NC(P(OCC)(OCC)=O)C9=CC=C(C=C9)F)C=C8)=O)=O)C(N6C5)=O)N=C4C=C3
- UNSPSC12131703