Antitumor agent-63 [1627600-90-1]

MedChem Express

Antitumor agent-63 [1627600-90-1]

10

1627600-90-1

Research Use Only

C38H46N4O18

846.79

Antitumor agent-63 (Compound 40), a 20 (S)-O-linked camptothecin (CPT) glycoconjugate, is an antitumor agent without toxicity towards normal cells. Antitumor agent-63 shows high stability and very weak direct topoisomerase I (Topo I) inhibition[1].

O[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)OC(N)=O)[C@H]1O[C@@H]([C@H]([C@@H]([C@@H](O2)CO)O)O)[C@H]2OCCOCCNC(O[C@]3(C4=C(COC3=O)C(N5C(C6=NC7=CC=CC=C7C=C6C5)=C4)=O)CC)=O

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