Antofloxacin [119354-43-7]

MedChem Express

Antofloxacin [119354-43-7]

10

119354-43-7

Research Use Only

C18H21FN4O4

376.38

Antofloxacin is a well tolerate, orally active and broad-spectrum 8-amino-fluoroquinolone with potent antibacterial activities. Antofloxacin shows superior antibacterial activity against gyrA mutation-positive H. pylori strains, especially in Asn87- mutated strains, compared to levofloxacin. Antofloxacin is a weak, reversible inhibitor of CYP1A2 for the research of infections caused by a diverse group of bacterial species[1][2][3].

O=C1C2=C(N)C(F)=C(N3CCN(CC3)C)C4=C2N(C=C1C(O)=O)[C@@H](C)CO4

12352200