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ProductsBack/AP1153 aptamer (sodium)

AP1153 aptamer (sodium)

Research Use Only

HY-160045

Product group Molecular Biology

Overview

Supplier
MedChem Express
Product Name
AP1153 aptamer (sodium)
Delivery Days Customer
14
Certification
Research Use Only
Scientific Description
AP1153 aptamer sodium is a DNA aptamer that specifically binds to the cholecystokinin receptor CCKBR (Kd: ~15 pM), but does not activate CCKBR-related signaling pathways. AP1153 aptamer sodium is internalized by pancreatic ductal adenocarcinoma (PDAC) cells in a receptor-mediated manner. AP1153 aptamer sodium can bioconjugate to the surface of fluorescent nanoparticles to facilitate nanoparticle delivery to PDAC tumors in vivo[1].
UNSPSC
41106300