Ap44mSe

MedChem Express

Ap44mSe

14

Research Use Only

C10H14N4Se

269.20

Ap44mSe is a selenosemicarbazone that effectively depletes cellular Fe, resulting in transferrin receptor-1 up-regulation, ferritin down-regulation, and increased expression of the potent metastasis suppressor, N-myc downstream regulated gene-1. Ap44mSe forms redox active Cu complexes that target the lysosome to induce lysosomal membrane permeabilization[1].

C/C(C1=NC=CC=C1)=N\NC(N(C)C)=[Se]

12352200