Ap4A [5542-28-9]

MedChem Express

Ap4A [5542-28-9]

5

5542-28-9

Research Use Only

C20H28N10O19P4

836.39

Ap4A (P1,P4-Di-(adenosine-5)-tetraphosphate) is a conserved second messenger in organisms ranging from bacteria to humans. Ap4A binds to the histidine triad nucleotide-binding protein 1 (HINT1) activates the transcription of genes downstream of MITF. Ap4A induces apoptosis[1][2].

O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3N)O[C@@H]1COP(OP(OP(OP(OC[C@H]4O[C@@H](N5C=NC6=C5N=CN=C6N)[C@H](O)[C@@H]4O)(O)=O)(O)=O)(O)=O)(O)=O

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