Apafant-d8 [1185101-22-7]

MedChem Express

Apafant-d8 [1185101-22-7]

999

1185101-22-7

Research Use Only

C22H14D8ClN5O2S

464.01

Apafant-d8 is the deuterium labeled Apafant. Apafant (WEB 2086) is a potent platelet-activating factor (PAF) antagonist, inhibits PAF binding to human PAF receptors with a Kiof 9.9 nM. Apafant increases the gene expression of PAF-r, alpha-globin, beta-globin, decreases the c-myb gene expression. Apafant shows a protective effect on alkyl-PAF-mediated lethalit[1][2][3].

O=C(N1C([2H])([2H])C([2H])([2H])OC([2H])([2H])C1([2H])[2H])CCC2=CC3=C(S2)N4C(CN=C3C5=C(C=CC=C5)Cl)=NN=C4C

12352200