Apaziquone

Biorbyt

Apaziquone [114560-48-4]

10

114560-48-4

Research Use Only

98.00%

C15H16N2O4

288.3

Apaziquone has potential antineoplastic and radiosensitization activities. It is converted to active metabolites in hypoxic cells by intracellular reductases, which are present in greater amounts in hypoxic tumor cells. The active metabolites alkylate DNA, resulting in apoptotic cell death.

C(O)C=1C2=C(N(C)C1/C=C/CO)C(=O)C=C(C2=O)N3CC3

-20°C

12352200