APBA2 antibody

GeneTex

APBA2 antibody

9

WB: 1 - 2 microg/mL. IHC-P: 10 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

APBA2

amyloid beta precursor protein binding family A member 2

D15S1518E, HsT16821, LIN-10, MGC:14091, MINT2, X11-BETA, X11L, amyloid-beta A4 precursor protein-binding family A member 2, X11-like protein, adapter protein X11beta, amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like), mint-2, neuron-specific X11L protein, neuronal munc18-1-interacting protein 2, phosphotyrosine-binding/-interacting domain (PTB)-bearing protein

Rabbit

IgG

Amyloid-beta A4 precursor protein-binding family A member 2

APBA2, a member of the X11 protein family, is a phosphotyrosine-binding domain protein and is a neuronal adapter protein that interacts with amyloid precursor protein (APP) and neuritic plaques in the brains of patients with Alzheimers disease. It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimers disease patients. APBA2 is believed to be involved in signal transduction processes and is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Recent reports suggest that it may also be a candidate gene for autism.

-20°C or -80°C,2°C to 8°C

12352203