APC Anti-Mouse FcepsilonRIalpha Antibody

Reddot Biotech

APC Anti-Mouse FcepsilonRIalpha Antibody

5

Flow Cytometry

Research Use Only

Monoclonal

44986

APC (Allophycocyanin)

Fcer1a

Fc receptor, IgE, high affinity I, alpha polypeptide

FcERI, Fce1a, Fcr-5, fcepsilonri, high affinity immunoglobulin epsilon receptor subunit alpha, fc-epsilon RI-alpha, igE Fc receptor subunit alpha

Hamster

IgG

High affinity immunoglobulin epsilon receptor subunit alpha

FcepsilonRIalpha is a transmembrane protein belonging to the Ig superfamily. FcepsilonRIalpha forms a tetrameric complex with one beta and two gamma-subunits. The FcepsilonRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcepsilonRIalpha, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcepsilonRIalpha subunit. - This is a APC Anti-Mouse FcepsilonRIalpha Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

Mouse

2°C to 8°C

41116161