Apc11 antibody [N2C3]

GeneTex

Apc11 antibody [N2C3]

9

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

ANAPC11

anaphase promoting complex subunit 11

anaphase promoting complex subunit 11 (yeast APC11 homolog); anaphase-promoting complex subunit 11; APC11; APC11 anaphase promoting complex subunit 11 homolog; Apc11p; cyclosome subunit 11; hepatocellular carcinoma-associated RING finger protein; HSPC214

Rabbit

IgG

Anaphase-promoting complex subunit 11

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of Lys-11-linked polyubiquitin chains and, to a lower extent, the formation of Lys-48- and Lys-63-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.

Human

-20°C or -80°C,2°C to 8°C

12352203