WB analysis of 25ng APC13 recombinant protein using GTX85186 APC13 antibody. Working concentration : 1microg/ml
WB analysis of 25ng APC13 recombinant protein using GTX85186 APC13 antibody. Working concentration : 1microg/ml
APC13 antibody
GTX85186
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetANAPC13
Overview
- SupplierGeneTex
- Product NameAPC13 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1 microg/mL. ICC/IF: 20 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID25847
- Target nameANAPC13
- Target descriptionanaphase promoting complex subunit 13
- Target synonymsanaphase-promoting complex subunit 13; APC13; cyclosome subunit 13; SWM1
- HostRabbit
- IsotypeIgG
- Protein IDQ9BS18
- Protein NameAnaphase-promoting complex subunit 13
- Scientific DescriptionCell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC13 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC13 promotes the stable association of APC3/Cdc27 and APC6/Cdc16 with the APC/C.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203