APG-1387
ORB1818721
CAS Number1570231-89-8
Product group Chemicals
Molecular Weight1157.4
Overview
- SupplierBiorbyt
- Product NameAPG-1387 [1570231-89-8]
- Delivery Days Customer10
- CAS Number1570231-89-8
- CertificationResearch Use Only
- Molecular FormulaC60H72N10O10S2
- Molecular Weight1157.4
- Scientific DescriptionAPG-1387, a bivalent SMAC mimetic, is an IAP antagonist that can induce proteasomal degradation of IAPs. APG-1387 sensitizes immune-mediated cell apoptosis in cancers. APG-1387 can be used for the research of hepatocellular carcinoma, ovarian cancer, and nasopharyngeal carcinoma.
- SMILESO=C(NC(C1=CC=CC=C1)C2=CC=CC=C2)[C@@H]3CC[C@H](CCN(S(C4=CC=CC(S(N(C[C@@H]5NC([C@H](C)NC)=O)CC[C@@H]6N([C@H](C(NC(C7=CC=CC=C7)C8=CC=CC=C8)=O)CC6)C5=O)(=O)=O)=C4)(=O)=O)C[C@@H]9NC([C@@H](NC)C)=O)N3C9=O
- UNSPSC12352200