Bio-Connect

APG-1387

ORB1818721
Biorbyt
CAS Number1570231-89-8
Product group Chemicals
Molecular Weight1157.4
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Overview

  • Supplier
    Biorbyt
  • Product Name
    APG-1387 [1570231-89-8]
  • Delivery Days Customer
    10
  • CAS Number
    1570231-89-8
  • Certification
    Research Use Only
  • Molecular Formula
    C60H72N10O10S2
  • Molecular Weight
    1157.4
  • Scientific Description
    APG-1387, a bivalent SMAC mimetic, is an IAP antagonist that can induce proteasomal degradation of IAPs. APG-1387 sensitizes immune-mediated cell apoptosis in cancers. APG-1387 can be used for the research of hepatocellular carcinoma, ovarian cancer, and nasopharyngeal carcinoma.
  • SMILES
    O=C(NC(C1=CC=CC=C1)C2=CC=CC=C2)[C@@H]3CC[C@H](CCN(S(C4=CC=CC(S(N(C[C@@H]5NC([C@H](C)NC)=O)CC[C@@H]6N([C@H](C(NC(C7=CC=CC=C7)C8=CC=CC=C8)=O)CC6)C5=O)(=O)=O)=C4)(=O)=O)C[C@@H]9NC([C@@H](NC)C)=O)N3C9=O
  • UNSPSC
    12352200

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