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Apicidin [183506-66-3]

A6132
LKT Laboratories
Estimated Purity≥98%
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Product group Chemicals
€ 922,00
10 mg
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Apicidin [183506-66-3]
  • Delivery Days Customer
    7
  • Estimated Purity
    ≥98%
  • Format
    Ethano (0.9 mg/mL)l, DMSO (0.9 mg/mL), Dichloromethane.; Slightly soluble in water, methanol
  • Scientific Description
    Cyclic tetrapeptide; HDAC inhibitor.
  • Storage Instruction
    4°C
  • UNSPSC
    12352200

References

  • Ahn MY, Ahn SG, Yoon JH. Apicidin, a histone deaceylase inhibitor, induces both apoptosis and autophagy in human oral squamous carcinoma cells. Oral Oncol. 2011 Nov;47(11):1032-8. PMID: 21856210. Brazelle W, Kreahling JM, Gemmer J, et al. Histone deacetylase inhibitors downregulate checkpoint kinase 1 expression to induce cell death in non-small cell lung cancer cells. PLoS One. 2010 Dec 14;5(12):e14335. PMID: 21179472. Kankaanranta H, Janka-Junttila M, Ilmarinen-Salo P, et al. Histone deacetylase inhibitors induce apoptosis in human eosinophils and neutrophils. J Inflamm (Lond). 2010 Feb 4;7:9. PMID: 20181093. Cheong JW, Chong SY, Kim JY, et al. Induction of apoptosis by apicidin, a histone deacetylase inhibitor, via the activation of mitochondria-dependent caspase cascades in human Bcr-Abl-positive leukemia cells. Clin Cancer Res. 2003 Oct 15;9(13):5018-27. PMID: 14581377.