Apilimod (hydrochloride) [870087-37-9]
HY-14644B
CAS Number870087-37-9
Product group Chemicals
Molecular Weight491.41
Overview
- SupplierMedChem Express
- Product NameApilimod (hydrochloride) [870087-37-9]
- Delivery Days Customer9
- CAS Number870087-37-9
- CertificationResearch Use Only
- Molecular FormulaC23H28Cl2N6O2
- Molecular Weight491.41
- Scientific DescriptionApilimod (STA 5326) hydrochloride is a PIKFYVE kinase inhibitor that promotes NLRP3 inflammatory vesicle activation and IL-1beta secretion. Apilimod hydrochloride has been shown to inhibit host cell proteases, which may prevent viral invasion but also block antiviral immune responses, potentially exacerbating immunosuppression in COVID-19.
- SMILESCC1=CC=CC(/C=N/NC2=CC(N3CCOCC3)=NC(OCCC4=CC=CC=N4)=N2)=C1.Cl.Cl
- UNSPSC12131703