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ProductsBack/Aplaviroc HCl

Aplaviroc HCl

ORB1146682

CAS Number461023-63-2

Product group Chemicals

Molecular Weight614.18

Overview

Supplier
Biorbyt
Product Name
Aplaviroc HCl [461023-63-2]
Delivery Days Customer
10
CAS Number
461023-63-2
Certification
Research Use Only
Molecular Formula
C33H44ClN3O6
Molecular Weight
614.18
Scientific Description
Aplaviroc, also known as AK-602; GW-873140; GW873140A; ONO-4128, is a CCR5 entry inhibitor for the potential treatment of HIV infection. Aplaviroc (GW873140) binds specifically to human cellular CC chemokine receptor 5 (CCR5) and demonstrates potent anti-human immunodeficiency virus activity in vitro in the subnanomolar range. In vitro studies show that aplaviroc selectively inhibits the binding of a particular monoclonal antibody, 45531, to CCR5.
SMILES
Cl.CCCCN1C2(CCN(CC3=CC=C(C=C3)OC4=CC=C(C(O)=O)C=C4)CC2)C(=O)NC(C(O)C5CCCCC5)C1=O
UNSPSC
12352200

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