APLF Polyclonal Antibody

Reddot Biotech

APLF Polyclonal Antibody

5

0.5 mg/ml

APLF

aprataxin and PNKP like factor

APFL; aprataxin- and PNK-like factor; aprataxin and PNK-like factor; apurinic-apyrimidinic endonuclease APLF; C2orf13; PALF; PNK and APTX-like FHA domain-containing protein; PNK and APTX-like FHA protein; Xip1; XRCC1-interacting protein 1; ZCCHH1; zinc finger, CX5CX6HX5H motif containing 1

C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks. Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3-5 exonuclease activities in vitro.

-20°C

12352203