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APOBEC3C antibody

GTX102164
GeneTex
ApplicationsImmunoPrecipitation, Western Blot
Product group Antibodies
ReactivityHuman
TargetAPOBEC3C
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Overview

  • Supplier
    GeneTex
  • Product Name
    APOBEC3C antibody
  • Delivery Days Customer
    9
  • Antibody Specificity
    Knockdown/Knockout validation was supported by references (PMID: 31448067)
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoPrecipitation, Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID27350
  • Target name
    APOBEC3C
  • Target description
    apolipoprotein B mRNA editing enzyme catalytic subunit 3C
  • Target synonyms
    A3C; APOBEC1L; apolipoprotein B editing enzyme catalytic polypeptide-like 3C; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C; ARDC2; ARDC4; ARP5; bK150C2.3; DNA dC->dU-editing enzyme APOBEC-3C; PBI; phorbolin I; probable DNA dC->dU-editing enzyme APOBEC-3C
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9NRW3
  • Protein Name
    DNA dC->dU-editing enzyme APOBEC-3C
  • Scientific Description
    This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • APOBEC3C, a nucleolar protein induced by genotoxins, is excluded from DNA damage sites. Constantin D et al., 2022 Feb, FEBS J
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  • Zika virus noncoding sfRNAs sequester multiple host-derived RNA-binding proteins and modulate mRNA decay and splicing during infection. Michalski D et al., 2019 Nov 1, J Biol Chem
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  • Extracellular vesicles mediate the horizontal transfer of an active LINE-1 retrotransposon. Kawamura Y et al., 2019, J Extracell Vesicles
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  • Upregulation of Ets1 expression by NFATc2 and NFKB1/RELA promotes breast cancer cell invasiveness. Kim GC et al., 2018 Nov 23, Oncogenesis
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  • A Single Nucleotide Polymorphism in Human APOBEC3C Enhances Restriction of Lentiviruses. Wittkopp CJ et al., 2016 Oct, PLoS Pathog
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  • Resources for the Comprehensive Discovery of Functional RNA Elements. Sundararaman B et al., 2016 Mar 17, Mol Cell
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