ELISA analysis of human apolipoprotein E protein using GTX42747 Apolipoprotein E antibody [WUE-4].
Apolipoprotein E antibody [WUE-4]
GTX42747
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse
TargetAPOE
Overview
- SupplierGeneTex
- Product NameApolipoprotein E antibody [WUE-4]
- Delivery Days Customer9
- Antibody SpecificityThis antibody recognizes an epitope within amino acids 140-160 of human Apolipoprotein E, a major component of very low-density lipoproteins (VLDLs).
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDWUE-4
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID348
- Target nameAPOE
- Target descriptionapolipoprotein E
- Target synonymsAD2; APO-E; ApoE4; apolipoprotein E; apolipoprotein E3; LDLCQ5; LPG
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThe protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jun 2016]
- ReactivityHuman, Mouse
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- Apolipoprotein E promotes lipid accumulation and differentiation in human adipocytes. Lasrich D et al., 2015 Sep 10, Exp Cell ResRead more