
IHC image of CSB-PA001948LA01HU diluted at 1:200 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.
APOO Antibody
CSB-PA001948LA01HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetAPOO
Overview
- SupplierCusabio
- Product NameAPOO Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID79135
- Target nameAPOO
- Target descriptionapolipoprotein O
- Target synonymsbrain my025; FAM121B; family with sequence similarity 121B; Mic23; MIC26; MICOS complex subunit MIC23; MICOS complex subunit MIC26; MICOS26; mitochondrial contact site and cristae organizing system subunit 26; My025
- HostRabbit
- IsotypeIgG
- Protein IDQ9BUR5
- Protein NameMICOS complex subunit MIC26
- Scientific DescriptionComponent of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a crucial role in crista junction formation and mitochondrial function (PubMed:25764979). Can promote cardiac lipotoxicity by enhancing mitochondrial respiration and fatty acid metabolism in cardiac myoblasts (PubMed:24743151). Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP)-dependent mechanism, probably as a VLDL-associated protein that is subsequently transferred to HDL (PubMed:16956892).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161