Apoptolidin
HY-126679
Overview
- SupplierMedChem Express
- Product NameApoptolidin [194874-06-1]
- Delivery Days Customer10
- CAS Number194874-06-1
- CertificationResearch Use Only
- Estimated Purity95.6
- Molecular FormulaC58H96O21
- Molecular Weight1129.37
- Scientific DescriptionApoptolidin is a polyketide isolated from Nocardiopsis ?bacteria [1] . Apoptolidin is a selective mitochondrial F 1 F O ATPase inhibitor. Apoptolidin is an apoptosis inducer and induces apoptotic cell death in cells transformed with the adenovirus type 12 oncogenes including ElA ( IC 50 =10-17 ng/ml) but not in normal cells [1] [2] .
- SMILESO[C@H]([C@](OC(/C(C)=C/C(C)=C/C(C)=C/[C@H]1C)=O)([H])C[C@@H]([C@H](CC/C=C(/C=C/[C@H]1O[C@H](O[C@H]2C)[C@H]([C@@H]([C@H]2OC)O)O)C)O)OC)[C@](O[C@@H]([C@@H]3C)C[C@H](COC)O[C@H](O[C@H]4C)C[C@](O)([C@H]4O[C@H](O[C@@H]5C)C[C@H]([C@@H]5O)OC)C)([C@@H]([C@H]3O)C)O
- Storage Instruction-20°C
- UNSPSC51202000