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Apoptolidin

HY-126679
MedChem Express
CAS Number194874-06-1
Product group Chemicals
Estimated Purity95.6
Molecular Weight1129.37
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Apoptolidin [194874-06-1]
  • Delivery Days Customer
    10
  • CAS Number
    194874-06-1
  • Certification
    Research Use Only
  • Estimated Purity
    95.6
  • Molecular Formula
    C58H96O21
  • Molecular Weight
    1129.37
  • Scientific Description
    Apoptolidin is a polyketide isolated from Nocardiopsis ?bacteria [1] . Apoptolidin is a selective mitochondrial F 1 F O ATPase inhibitor. Apoptolidin is an apoptosis inducer and induces apoptotic cell death in cells transformed with the adenovirus type 12 oncogenes including ElA ( IC 50 =10-17 ng/ml) but not in normal cells [1] [2] .
  • SMILES
    O[C@H]([C@](OC(/C(C)=C/C(C)=C/C(C)=C/[C@H]1C)=O)([H])C[C@@H]([C@H](CC/C=C(/C=C/[C@H]1O[C@H](O[C@H]2C)[C@H]([C@@H]([C@H]2OC)O)O)C)O)OC)[C@](O[C@@H]([C@@H]3C)C[C@H](COC)O[C@H](O[C@H]4C)C[C@](O)([C@H]4O[C@H](O[C@@H]5C)C[C@H]([C@@H]5O)OC)C)([C@@H]([C@H]3O)C)O
  • Storage Instruction
    -20°C
  • UNSPSC
    51202000

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