Apoptosis inducer 34 [582314-48-5]
HY-116692
CAS Number582314-48-5
Product group Chemicals
Molecular Weight336.21
Overview
- SupplierMedChem Express
- Product NameApoptosis inducer 34 [582314-48-5]
- Delivery Days Customer5
- CAS Number582314-48-5
- CertificationResearch Use Only
- Molecular FormulaC17H15Cl2NO2
- Molecular Weight336.21
- Scientific DescriptionApoptosis inducer 34 (Compound 4) is a small molecule compound that induces apoptosis by directly activating the intrinsic apoptotic pathway. Apoptosis inducer 34 promotes Apaf-1 oligomerization to form mature apoptosomes, thereby activating caspase-9 and caspase-3. It significantly activates the apoptotic pathway in Jurkat cells by enhancing the cytochrome c-dependent apoptotic signaling pathway, inducing PARP cleavage and chromosomal DNA fragmentation. Furthermore, Apoptosis inducer 34 exhibits low toxicity to normal cells, demonstrating potential for selective targeting of cancer cells. Apoptosis inducer 34 is a promising candidate for studying cancer related to apoptotic pathways[1].
- SMILESO=C(O[C@H]1CCC2=C1C=CC=C2)NCC3=CC=C(Cl)C(Cl)=C3
- UNSPSC12352200