Apratastat [287405-51-0]

TargetMol Chemicals

Apratastat [287405-51-0]

44

287405-51-0

Research Use Only

Apratastat

C17H22N2O6S2

414.5

Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-alpha converting enzyme (TACE) and matrix metalloproteinases (MMPs) and it also can potently inhibit the release of TNF-alpha in vitro, ex vivo, and in vivo with IC50s of 144 ng/mL in vitro and 81.7 ng/mL ex vivo, respectively[1].

3 years

CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCC#CCO)cc1

-20°C

12352200