Apremilast-d5 [1258597-47-5]

MedChem Express

Apremilast-d5 [1258597-47-5]

9

1258597-47-5

Research Use Only

99.26

C22H19D5N2O7S

465.53

Apremilast-d5 is a deuterium labeled Apremilast. Apremilast is an orally available inhibitor of type-4 cyclic nucleotide phosphodiesterase (PDE-4) with an IC50 of 74 nM. Apremilast inhibits TNF-alpha release by lipopolysaccharide (LPS) with an IC50 of 104 nM[1].

CC(NC1=CC=CC(C(N2[C@@H](C3=CC=C(OC)C(OC([2H])([2H])C([2H])([2H])[2H])=C3)CS(=O)(C)=O)=O)=C1C2=O)=O

-20°C,2°C to 8°C

12352200