Apricoxib [197904-84-0]

TargetMol Chemicals

Apricoxib [197904-84-0]

72

197904-84-0

Chemical

Research Use Only

Apricoxib

C19H20N2O3S

356.44

Apricoxib, also known as Benzenesulfonamide 42(4ethoxyphenyl)4methyl1Hpyrrol1yl, is an orally bioavailable nonsteroidal anti-inflammatory agent (NSAID) with potential antiangiogenic and antineoplastic activities. Apricoxib binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), thereby inhibiting the conversion of arachidonic acid into prostaglandins. Apricoxib-mediated inhibition of COX-2 may induce tumor cell apoptosis and inhibit tumor cell proliferation and tumor angiogenesis. COX-related metabolic pathways may represent crucial regulators of cellular proliferation and angiogenesis.

3 years

CC=1C=C(N(C1)C2=CC=C(S(N)(=O)=O)C=C2)C3=CC=C(OCC)C=C3

-20°C

12352200