Aprocitentan-d4

MedChem Express

Aprocitentan-d4

10

Research Use Only

97.39

C16H10D4Br2N6O4S

550.22

Aprocitentan-d 4 is a deuterium labeled Aprocitentan. Aprocitentan is a major and pharmacologically active metabolite of Macitentan. Aprocitentan is an orally active dual ETA/ETB antagonist with IC50s of 3.4 nM and 987 nM, and pA2 valus of 6.7 and 5.5, respectively. Aprocitentan is an antihypertensive agent [1] .

O=S(N)(NC1=NC=NC(OC([2H])([2H])C([2H])([2H])OC2=NC=C(Br)C=N2)=C1C3=CC=C(Br)C=C3)=O

-20°C,2°C to 8°C

12352200