APS-2-79 (hydrochloride) [2002381-31-7]
HY-100627A
CAS Number2002381-31-7
Product group Chemicals
Molecular Weight423.89
Overview
- SupplierMedChem Express
- Product NameAPS-2-79 (hydrochloride) [2002381-31-7]
- Delivery Days Customer10
- CAS Number2002381-31-7
- CertificationResearch Use Only
- Molecular FormulaC23H22ClN3O3
- Molecular Weight423.89
- Scientific DescriptionAPS-2-79 hydrochloride is a KSR-dependent MEK antagonist. APS-2-79 inhibits ATPbiotin binding to KSR2 within the KSR2-MEK1 complexe with an IC50 of 120 nM. APS-2-79 makes the stabilization of the KSR inactive state antagonizes oncogenic Ras-MAPK signaling[1].
- SMILESCC1=CC(OC2=CC=CC=C2)=CC=C1NC3=C4C=C(OC)C(OC)=CC4=NC=N3.Cl
- UNSPSC12352200