APTX Antibody, Biotin conjugated

Cusabio

APTX Antibody, Biotin conjugated

20

ELISA

Research Use Only

Polyclonal

Biotin

APTX

aprataxin

AOA, AOA1, AXA1, EAOH, EOAHA, FHA-HIT, aprataxin, forkhead-associated domain histidine triad-like protein

Rabbit

IgG

Aprataxin

DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5-phosphate termini, resulting in the production of 5-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5-monophosphoramidate (AMP-NH(2)) and diadenosine tetraphosphate (AppppA), but with lower catalytic activity.

Human

-20°C or -80°C

41116161