APX-115 [1395946-75-4]

MedChem Express

APX-115 [1395946-75-4]

10

1395946-75-4

Research Use Only

99.08

C17H18ClN3O

315.80

APX-115 (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with Ki values of 1.08 microM, 0.57 microM, and 0.63 microM for Nox1, Nox2 and Nox4, respectively. APX-115 effectively prevents kidney injury[1].

OC1=C(CCC)C(C2=CC=CC=C2)=NN1C3=NC=CC=C3.Cl

2°C to 8°C

12352200