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APX-115 free base [1270084-92-8]

APX-115 free base [1270084-92-8]

T10353
TargetMol Chemicals
CAS Number1270084-92-8
Product group Chemicals
Estimated Purity99.03%
Molecular Weight279.34
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    APX-115 free base [1270084-92-8]
  • Delivery Days Customer
    4
  • CAS Number
    1270084-92-8
  • Certification
    Research Use Only
  • Chemical Name
    APX-115 free base
  • Estimated Purity
    99.03%
  • Molecular Formula
    C17H17N3O
  • Molecular Weight
    279.34
  • Scientific Description
    APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with inhibition constants (Kis) of 1.08 microM, 0.57 microM, and 0.63 microM for Nox1, Nox2, and Nox4, respectively, and it effectively prevents kidney injury.
  • Shelf life instruction
    3 years
  • SMILES
    CCCc1c(O)n(nc1-c1ccccc1)-c1ccccn1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200