APY29 [1216665-49-4]
HY-17537
CAS Number1216665-49-4
Product group Chemicals
Estimated Purity99.90
Molecular Weight332.36
Overview
- SupplierMedChem Express
- Product NameAPY29 [1216665-49-4]
- Delivery Days Customer10
- CAS Number1216665-49-4
- CertificationResearch Use Only
- Estimated Purity99.90
- Molecular FormulaC17H16N8
- Molecular Weight332.36
- Scientific DescriptionAPY29, an ATP-competitive inhibitor, is an allosteric modulator of IRE1alpha which inhibits IRE1alpha autophosphorylation by binding to the ATP-binding pocket with IC50 of 280 nM. APY29 acts as a ligand that allosterically activates IRE1alpha adjacent RNase domain[1].
- SMILESC1(NC2=CC=C3N=CNC3=C2)=NC=CC(NC4=NNC(C5CC5)=C4)=N1
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200