Bio-Connect

AR-C117977 [216685-07-3]

HY-114602
MedChem Express
CAS Number216685-07-3
Product group Chemicals
Molecular Weight468.63
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Overview

  • Supplier
    MedChem Express
  • Product Name
    AR-C117977 [216685-07-3]
  • Delivery Days Customer
    5
  • CAS Number
    216685-07-3
  • Certification
    Research Use Only
  • Molecular Formula
    C25H28N2O3S2
  • Molecular Weight
    468.63
  • Scientific Description
    AR-C117977 is a potent monocarboxylate transporter (MCT1) inhibitor. AR-C117977 prolongs the survival of skin and heart sllograft. AR-C117977 inhibits the development of transplant arteriosclerosis in aortic allografts partially, but was unable to inhibit alloantibody production after transplantation. AR-C117977 shows potent immunosuppressive properties in vivo effectively preventing acute but not chronic allograft rejection in the mouse[1].
  • SMILES
    O=C1N(CC(C)C)C2=C(C(SCCCO)=C(CC3=C4C=CC=CC4=CC=C3)S2)C(N1C)=O
  • UNSPSC
    12352200