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AR-R17779 (hydrochloride) [178419-42-6]

HY-135483A
MedChem Express
CAS Number178419-42-6
Product group Chemicals
Estimated Purity99.0
Molecular Weight218.68
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Overview

  • Supplier
    MedChem Express
  • Product Name
    AR-R17779 (hydrochloride) [178419-42-6]
  • Delivery Days Customer
    5
  • CAS Number
    178419-42-6
  • Certification
    Research Use Only
  • Estimated Purity
    99.0
  • Hazard Information
    h315, h318, h335
  • Molecular Formula
    C9H15ClN2O2
  • Molecular Weight
    218.68
  • Scientific Description
    AR-R17779 hydrochloride is a potent and selective full agonist of nAChR, with Kis of 92 and 16000 nM for alpha7 and alpha4beta2 subtype, respectively. AR-R17779 hydrochloride can improve learning and memory in rats. AR-R17779 hydrochloride also has anxiolytic activity. AR-R17779 hydrochloride can reduce inflammation by activating antiinflammatory cholinergic (vagal) pathways[1][2][4].
  • SMILES
    O=C(NC1)O[C@@]21CN3CCC2CC3.[H]Cl
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200