Aranorosinol B [145147-05-3]

Name: Aranorosinol B [145147-05-3]
SKU: AG-CN2-0494_A27
Availability: BackOrder

AG-CN2-0494

CAS Number145147-05-3

Product group Chemicals

Estimated Purity>94%

Molecular Weight477.6

Overview

Supplier
AdipoGen Life Sciences
Product Name
Aranorosinol B
Delivery Days Customer
10
CAS Number
145147-05-3
Certification
Research Use Only
Estimated Purity
>94%
Hazard Information
Warning
Molecular Formula
C26H39NO7
Molecular Weight
477.6
Scientific Description
Antibiotic. Moderate antibacterial and antifungal agent. Inhibits the autophosphorylation of histidine kinase WalK/YycG. The WalK/WalR (aka YycG/YycF) two-component system is indispensable in the signal transduction pathway for the cell-wall metabolism/synthesis. - Chemical. CAS: 145147-05-3. Formula: C26H39NO7. MW: 477.6. Isolated from Phoma sp. Antibiotic. Moderate antibacterial and antifungal agent. Inhibits the autophosphorylation of histidine kinase WalK/YycG. The WalK/WalR (aka YycG/YycF) two-component system is indispensable in the signal transduction pathway for the cell-wall metabolism/synthesis.
SMILES
CCCCCC[C@@H](C)/C=C(C)/C=C/C(N[C@@H]1C(O)O[C@]2([C@H](O3)[C@H]3C(CC(C)=O)(O)[C@H]4[C@@H]2O4)C1)=O
Storage Instruction
-20°C,2°C to 8°C
UNSPSC
12352200

Aranorosinol A and Aranorosinol B, two new metabolites from Pseudoarachniotus roseus: production, isolation, structure elucidation and biological properties: K. Roy, et al.; J. Antibiot. 45, 1592 (1992)
Isolation and characterization of inhibitors of the essential histidine kinase, YycG in Bacillus subtilis and Staphylococcus aureus: T. Watanabe, et al.; J. Antibiot. 56, 1045 (2003)
Cytotoxic acyl amides from the soil fungus Gymnascella dankaliensis: L. Hammerschmidt, et al.; Bioorg. Med. Chem. 23, 712 (2015)