ARC19499 [1350667-54-7]
HY-153480
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product NameARC19499 [1350667-54-7]
- Delivery Days Customer10
- CAS Number1350667-54-7
- CertificationResearch Use Only
- Estimated Purity93.65
- Molecular Weight11078.95
- Scientific DescriptionARC19499 is an aptamer that inhibits tissue factor pathway inhibitor (TFPI) , thereby enabling clot initiation and propagation via the extrinsic pathway. The core aptamer binds tightly and specifically to TFPI. ARC19499 blocks TFPI inhibition of both factor Xa and the TF/factor VIIa complex. ARC19499 corrects thrombin generation in hemophilia A and B plasma and restores clotting in FVIII-neutralized whole blood.
- SMILES[ARC19499]
- Storage Instruction-20°C
- UNSPSC41115811