Bio-Connect

Arginase-2/ARG2 Protein, Mouse, Recombinant (His & SUMO)

Research Use Only
TMPH-02526
TargetMol Chemicals
Product group Molecular Biology
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Arginase-2/ARG2 Protein, Mouse, Recombinant (His & SUMO)
  • Delivery Days Customer
    16
  • Certification
    Research Use Only
  • Scientific Description
    May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synthase (NOS). Arginine metabolism is a critical regulator of innate and adaptive immune responses. Seems to be involved in negative regulation of the survival capacity of activated CD4(+) and CD8(+) T cells. May suppress inflammation-related signaling in asthmatic airway epithelium. May contribute to the immune evasion of H.pylori by restricting M1 macrophage activation and polyamine metabolism. May play a role in promoting prenatal immune suppression. Regulates RPS6KB1 signaling, which promotes endothelial cell senescence and inflammation and implicates NOS3/eNOS dysfunction. Can inhibit endothelial autophagy independently of its enzymatic activity implicating mTORC2 signaling. Involved in vascular smooth muscle cell senescence and apoptosis independently of its enzymatic activity.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352204