arigoQIK(r) Human IDO1 / INDO ELISA Development Kit

Arigo Biolaboratories

arigoQIK(r) Human IDO1 / INDO ELISA Development Kit

23

ELISA

Intra-Assay CV: < 10%Inter-Assay CV: < 10%

15.63 pg/mL

Research Use Only

HRP

Indoleamine 2,3-dioxygenase 1

This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011]

-20°C,2°C to 8°C

41116100

Human