Bio-Connect

ARIH2 Polyclonal Antibody

Research Use Only
RD76649A
Reddot Biotech
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse
TargetARIH2
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    ARIH2 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.6 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID10425
  • Target name
    ARIH2
  • Target description
    ariadne RBR E3 ubiquitin protein ligase 2
  • Target synonyms
    all-trans retinoic acid inducible RING finger; ARI2; ariadne homolog 2; E3 ubiquitin-protein ligase ARIH2; protein ariadne-2 homolog; RING-type E3 ubiquitin transferase ARIH2; TRIAD1
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    TRIAD1, also known as ARIH2 (ariadne homolog 2) or ARI2, is a 493 amino acid protein that contains one IBR-type zinc finger and two RING-type zinc fingers and belongs to the ariadne subfamily of RBR proteins. Localized to the nucleus, TRIAD1 interacts with UBE2L3 and is thought to act as an E3 ubiquitin-protein ligase, functioning to accept ubiquitin from E2 ubiquitin-conjugating enzymes and transfer the acquired ubiquitin residue to target substrates. TRIAD1 is subject to post-translational DNA damage-dependent phosphorylation, probably by ATM or ATR. The gene encoding TRIAD1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203