Arimoclomol

MedChem Express

Arimoclomol [289893-25-0]

10

289893-25-0

Research Use Only

C14H20ClN3O3

313.78

Arimoclomol (BRX-220 free base) is an orally active co-inducer of heat shock proteins ( HSP ) [1] . Arimoclomol protects motor neurons by enhancing Hsp expression, thus directly affecting protein aggregation and clearance of misfolded assemblies via the proteasome-ubiquitin system [2] .Arimoclomol can be used for the study of Niemann-Pick disease type C.

Cl/C(C1=C[N+]([O-])=CC=C1)=N\OC[C@H](O)CN2CCCCC2

12352200