ARMET/MANF, Human (HEK293, Fc)

MedChem Express

ARMET/MANF, Human (HEK293, Fc)

10

Research Use Only

MANF

mesencephalic astrocyte derived neurotrophic factor

ARMET, ARP, DDDS, mesencephalic astrocyte-derived neurotrophic factor, arginine-rich, mutated in early stage tumors

cDNA FLJ77177, highly similar to Homo sapiens arginine-rich, mutated in early stage tumors (ARMET), mRNA

ARMET/MANF Protein is an evolutionary conserved endoplasmic reticulum stress- (ERS-) related protein. ARMET/MANF has a protective effect on central nervous system diseases and plays an important role in several metabolic diseases. It is mainly localized to the luminal endoplasmic reticulum (ER) as an ER chaperone protein, mainly interacting with BiP and Reticulon 1-C. Meanwhile, MANF can prevent ER stress-mediated cell death in neurons and other tissues. ARMET/MANF Protein, Human (HEK293, Fc) is the recombinant human-derived ARMET/MANF protein, expressed by HEK293 , with C-hFc labeled tag.

41116100

Human